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Book Panama City Vacations

Save up to $374^ on your trip when booking flight + hotel together

Top Panama City vacation deals

Toscana Inn
AC Hotel by Marriott Panama City
The Executive Hotel
Hotel El Panama by Faranda Grand
Sortis Hotel, Spa & Casino, Autograph Collection

Panama City Travel Guide

Get going on your spectacular Panama City vacation! Let the team here at Orbitz bundle up irrestistible hotel and flight deals. How do savings of up to $369^ grab you? Just select your preferred hotels, airfares, rental cars and experiences and you'll have a little extra change bouncing around in your pockets! On top of all that, you'll be thrilled to discover that you can customize your getaway by picking from 500 partner airlines and no less than 500,000 accommodations globally. There truly is something for everyone. Our packages offer endless options to customize your trip along with an experience you'll never forget.

Where is Panama City?

Learning a little about your destination before you get there is a good way to prepare for your vacation. Ready to find out where Panama City is on the world map? It's the national capital city of Panama and located about 6 miles to the southwest of the significant city of San Miguelito.

Car Rentals in Panama City

Incredible adventures are just around the bend with car rentals in Panama City. Ready to discover the region from the comfort of your own ride? Flying in? Fox Rental Cars at Tocumen International Airport is the vendor to rent from after you escape baggage claim. Budget is right in the center of the city. Simply make your way to El Cangrejo 55Th Street. Why don't you also try Avis? They can be found at Calle D, El Cangrejo, Victoria Hotel.

Where to stay in Panama City – Hotel Accommodation

Orbitz lists a fantastic range of 131 hotels in Panama City. Pick one and start crafting your escape to the national capital of Panama. If you like all things luxury, the Villa Palma Boutique Hotel is an ideal option. Alternatively, try the American Trade Hotel. Or, if you're traveling on a budget, have a look at the Villa Michelle and the Hotel Covadonga.

Nearest Airports to Panama City

Is there anything better than jumping on a plane, binging on movies and knowing that the beginning of your vacation is just hours away? Once you touch down at Tocumen International Airport (PTY), the closest airport to Panama City, you'll be just 11 miles from the center of town.

Popular Places to Visit Near Panama City

If you've got a spare day and don't mind traveling 16 miles, head on over to Gamboa. This happening destination has a world of activities on offer. If you want to spend a whole day in this area, stop by Soberania National Park in the morning. Next head on over to Culebra Cut and the Summit Botanical Gardens & Zoo. Situated 30 miles away, Sabanitas is another favored destination. When you come here, be sure to check out Galeta Island Marine Education Center, Colon 2000 and Gatun Eco Adventures.

No Cancellation Fees

Packed your bags, booked your vacation but now you can't go? Don't sweat it — we make canceling your plans a breeze by not asking you for a fee.^ Act soon and your selected hotel and airline might do the same!

Top rated hotels for your Panama City vacation

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