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You'll discover it approximately 150 miles southeast of Springfield, the state capital of Illinois, and about 20 miles east of Marion.
This corner of Southeast Illinois has a population of around 9,000 residents, some of whom will surely be willing to offer you some exciting travel tips.
Push play on your favorite tunes and discover Harrisburg from the freedom of your own wheels. You'll find some of the best value car rentals in Harrisburg on Orbitz.
Staying int he downtown area? Start your drive on a high by beginning your trip from the middle of the city. You'll find Enterprise located at 540 N Commercial St.
If you're flying in to Harrisburg, you'll likely be touching down at Southern Illinois Airport (MDH). Grab a coffee and find your bearings after exiting the plane. This is the nearest airport, sitting 40 miles from the center of town.
Plans can change in a heartbeat, which is one of the reasons we won't request a fee if you have to cancel or adjust your booking.^ However, it might be prudent to check if your chosen airline and hotel will do the same.